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Acute renal failure pathophysiology

Acute Renal Failure And Sepsis

Acute kidney failure occurs when your kidneys suddenly become unable to filter waste products from your blood. When your kidneys lose their filtering ability, dangerous levels of wastes may accumulate, and your blood's chemical makeup may get out of balance Acute Kidney Injury (AKI) is the term that has recently replaced the term ARF. AKI is defined as an abrupt (within hours) decrease in kidney function, which encompasses both injury (structural damage) and impairment (loss of function). It is a syndrome that rarely has a sole and distinct pathophysiology Acute Renal Failure Can be classified as prerenal failure, intrarenal failure, or postrenal failure. Can be reversible. Can lead to chronic renal failure. Caused by obstruction, poor circulation, or kidney disease. Interruption in flow can lead to serious failure. Phases of Acute Renal Failure: Oliguric, Diuretic, Recovery (ODR) Oliguric Phase Oliguria - Decreased urine output [

Despite the availability of modern techniques, mortality continues to be high in acute renal failure (ARF). A more specific form of therapy will not be available until the basic pathophysiologic mechanisms in ARF are known. Tubular obstruction, increased tubular permeability and marked renal.. Purpose of review: Acute renal failure is a serious condition that affects as many as 20% of ICU patients. The most common causes of acute renal failure in the ICU patient are severe sepsis and septic shock. The mortality of acute renal failure in septic critically ill patients remains high despite our increasing ability to support vital organs Explain the pathophysiology of acute renal failure. Include prerenal intrarenal and postrenal causes. According to the Mayo Clinic Staff (2012), acute kidney renal failure occurs abruptly when your kidneys lose their filtering abilities and cannot filter waste products from your blood Acute kidney injury (AKI), previously called acute renal failure (ARF), is a condition of sudden kidney failure in patients with or without preexisting chronic kidney disease (CKD); severe kidney dysfunction within a few hours or days results in a significant decrease (oliguria) or complete elimination of urine (anuria), with electrolyte imbalance, often requiring hemodialysis

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The Pathophysiology Of Acute Renal Failure 1. ACUTE RENAL FAILURE The glomerular filtration rate is reduced, Sudden retention of endogenous and exogenous metabolites (urea, potassium, phosphate, sulfate, creatinine, administered drugs), The urine volume is usually low (under 400 mL/day). 2 Acute renal failure occurs in 5 percent of hospitalized patients. Etiologically, this common condition can be categorized as prerenal, intrinsic or postrenal. Most patients have prerenal acute.

Acute kidney failure - Symptoms and causes - Mayo Clini

  1. g complication of nephrotic syndrome (NS). Causes include rapid progression of the original glomerular disease, renal vein thrombosis and allergic interstitial nephritis (antibiotics, diuretics, NSAIDs)
  2. This article summarizes the pathophysiology of acute renal failure from both experimental and clinical points of view. Prerenal acute renal failure is an appropriate physiologic response to renal hypoperfusion and can complicate any disease characterized by either true hypovolemia or a reduction in the effective circulating volume. In acute tubular necrosis, the abrupt fall in glomerular.
  3. Renal failure results when the kidneys cannot remove the body's metabolic wastes or perform their regulatory functions. Acute renal failure (ARF) is a rapid loss of renal function due to damage to the kidneys. Acute renal failure is also known today as acute kidney injury (AKI)

Acute Kidney Injury: Definition, Pathophysiology and

  1. al kidney damage. During this time, there is modulation and adaptation in the still-functional glomeruli, which keeps the kidneys functioning normally for as long as possible
  2. In the early stages of chronic kidney disease, you may have few signs or symptoms. Chronic kidney disease may not become apparent until your kidney function is significantly impaired. Treatment for chronic kidney disease focuses on slowing the progression of the kidney damage, usually by controlling the underlying cause
  3. ate excess salts, fluids, and waste materials from the blood. This eli
  4. Acute renal failure (ARF) is a syndrome that can be defined as an abrupt decrease in renal function sufficient to result in retention of nitrogenous waste in the body. ARF can result from a decrease of renal blood flow, intrinsic renal parenchymal diseases, or obstruction of urine flow. There has been little progress in preventing and treating.
  5. uria or abnormal biopsy) O

Acute kidney failure is when your kidneys stop working suddenly. Doctors sometimes call it acute renal failure. It can happen over just a few hours or days. Acute kidney failure isn't always.. End stage kidney disease occurs when about 90 percent of kidney function has been lost. People with kidney failure may experience nausea, vomiting, weakness, fatigue, confusion, difficulty concentrating and loss of appetite. It can be diagnosed by blood and urine tests. Find answers about kidney disease during the COVID-19 outbreak here

Acute Renal Failure Pathophysiology Simplified - QD Nurse

Pathophysiology of Acute Renal Failure JAMA Internal

Acute renal failure 1. DEFINITIONS Acute renal failure is a sudden reduction in kidney function that results in nitrogenous wastes accumulating in the blood. 2. ETIOLOGY 3. Problems affecting the flow of blood before itreaches the kidneys 1) Dehydration vomiting, diarrhea, water pills, or bloodloss Other causes of kidney disease include. a genetic disorder that causes many cysts to grow in the kidneys, polycystic kidney disease (PKD). an infection. a drug that is toxic to the kidneys. a disease that affects the entire body, such as diabetes or lupus. NIH external link. . Lupus nephritis is the medical name for kidney disease caused by lupus Kidney Failure. Organ failure, including kidney failure, is a hallmark of sepsis. As the body is overwhelmed, its organs begin to shut down, causing even more problems. The kidneys are often among the first to be affected. According to the National Kidney Foundation, one of the major causes of acute kidney injury (also called AKI) is sepsis and. This article summarizes the pathophysiology of acute renal failure from both experimental and clinical points of view. Prerenal acute renal failure is an appropriate physiologic response to renal hypoperfusion and can complicate any disease characterized by either true hypovolemia or a reduction in the effective circulating volume Acute renal failure (ARF), characterized by sudden loss of the ability of the kidneys to excrete wastes, concentrate urine, conserve electrolytes, and maintain fluid balance, is a frequent clinical problem, particularly in the intensive care unit, where it is associated with a mortality of between 50% and 80%

Post-renal Acute Renal Failure. Urinary tract obstruction is responsible for less than 5% of cases of acute renal failure. As one kidney can compensate for the other poorly functioning kidney, a bilateral urinary tract obstruction is required for it to cause the kidney's to fail Pathophysiology of Nephrotoxic Acute Renal Failure H umans are exposed intentionally and unintentionally to a variety of diverse chemicals that harm the kidney. As the list of drugs, natural products, industrial chemicals and environ-mental pollutants that cause nephrotoxicity has increased, it ha

Glomerulonephritis in children chronic kidney failure

The pathogenesis of septic acute renal failur

Renal disease pathophysiology and treatment: contributions

The Pathophysiology of Acute Renal Failure - 556 Words

Acute kidney injury (AKI), also known as Acute Renal Failure, is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. AKI causes a build-up of waste products in your blood and makes it hard for your kidneys to keep the right balance of fluid in your body. AKI can also affect other organs such as the brain, heart, and lungs Now, we will determine how severe the condition is and in doing so, you have to know the two conditions of acute renal failure which are: Extrarenal failure (prerenal) - 20:1 ratio for BUN/creatinine. Intrarenal failure - 10:1 ratio for BUN/creatinine. The difference between the two is their location Chronic kidney disease (CKD) is defined as the presence of kidney damage or an estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73 mt2, persisting for 3 months or more, irrespective of the cause.[1] It is a state of progressive loss of kidney function ultimately resulting in the need for renal replacement therapy (dialysis or transplantation) Urinary tract problems. Sometimes the kidneys can stop working very suddenly (within two days). This type of kidney failure is called acute kidney injury or acute renal failure. Common causes of acute renal failure include: Heart attack. Illegal drug use and drug abuse. Not enough blood flowing to the kidneys

Acute kidney injury pathology and pathophysiology: a

  1. Acute Kidney Failure Prerenal Causes. Prerenal failure is the most common type of acute renal failure (60% to 70% of all cases). The kidneys do not receive enough blood to filter. Prerenal failure can be caused by the following conditions: Dehydration: From vomiting, diarrhea, water pills, or blood loss
  2. Kidney diseases are the ninth leading cause of death in the United States.; About 37 million US adults are estimated to have CKD and most are undiagnosed.; 40% of people with severely reduced kidney function are not aware of having CKD.; Every 24 hours, 350 people begin dialysis treatment for kidney failure. In the United States, diabetes and high blood pressure are the leading causes of.
  3. An intrinsic renal state is a condition in which kidney damage has occurred but not due to lack of adequate kidney blood flow (a prerenal state) or obstruction of urine outflow (a postrenal state). Advertisements. As with both prerenal and postrenal conditions, an intrinsic renal state will eventually lead to a loss of GFR
  4. Kidney disease can affect children in various ways, ranging from treatable disorders without long-term consequences to life-threatening conditions. Acute kidney disease develops suddenly, lasts a short time, and can be serious with long-lasting consequences or may go away completely once the underlying cause has been treated
  5. The Pathophysiology Of Acute Renal Failure Bayu_F_Wibowo. Slide shere mariabraga. Hemodialysis procedure IPMS- KMU KPK PAKISTAN. X-RAYS ON PNEUMONIA BY DR BASHIR AHMED DAR ASSOCIATE PROFESSOR MEDICINE SOPOR... Prof Dr Bashir Ahmed Dar. Renal pathology raj kumar. Renal pathology..at glance.
  6. Pathophysiology. The pathophysiologic mechanisms that lead to chronic kidney disease (CKD) stem from the underlying etiologies responsible for the primary renal damage. The initial insult is responsible for a decrease in the number of functional nephrons. However, beyond that initial insult, a form of maladaptive systemic and renal response.

The Pathophysiology Of Acute Renal Failur

  1. Chronic kidney disease - a progressive type of kidney problem that gets worse over time - is the most common type of kidney disease. It affects about 30 million Americans, according to the.
  2. Stage 3 kidney disease symptoms. You may not notice symptoms of chronic kidney problems in stages 1 and 2, but the signs start to become more noticeable in stage 3. Some of the symptoms of CKD.
  3. Acute kidney injury is defined as an abrupt (within 48 hours) reduction in kidney function based on an elevation in serum creatinine level, a reduction in urine output, the need for renal.
  4. Acute kidney injury (AKI)—or acute renal failure (ARF), as it was previously termed—is defined as an abrupt or rapid decline in renal filtration function. This condition is usually marked by a rise in serum creatinine concentration or by azotemia (a rise in blood urea nitrogen [BUN] concentration). [ 1

Chronic kidney disease, also called CKD, is a type of long-term damage to the kidneys.It's characterized by permanent damage that progresses on a scale of five stages. Stage 1 means you have the. What is diabetic kidney disease? Diabetic kidney disease is a type of kidney disease caused by diabetes. Diabetes is the leading cause of kidney disease. About 1 out of 3 adults with diabetes has kidney disease. 1. The main job of the kidneys is to filter wastes and extra water out of your blood to make urine Depending on the underlying cause, some types of kidney disease can be treated. Often, though, chronic kidney disease has no cure. Treatment usually consists of measures to help control signs and symptoms, reduce complications, and slow progression of the disease

Chronic renal disease | The BMJ

Vascular disease generally causes a slow progression of kidney failure, rather than acute renal failure. But, after a period of a slow progression without symptoms or obvious effects, vascular disease may suddenly cause symptoms that are similar to the symptoms of acute renal failure Anemia is common in people with CKD, especially among people with more advanced kidney disease. More than 37 million American adults may have CKD, 1 and it is estimated that more than 1 out of every 7 people with kidney disease have anemia. 2. Most people who have kidney failure—when kidney damage is so advanced that less than 15 percent of. Causes of Acute Renal Failure • Intra-renal failure - Results from acute damage to renal structures - Possible causes: • acute glomerulonephritis, pyelonephritis • May also result from acute tubular necrosis (ATN) • damage of kidney structure from exposure to toxins, solvents, drugs and heavy metals; ATN is the most common cause of. End-of-Life Kidney Failure Signs. Sometimes referred to as renal failure, kidney failure is the final stage of chronic kidney disease. The patient's kidneys gradually lose their ability to filter excess fluids from the blood, creating a build-up within the body. At this point, the patient needs dialysis or a kidney transplant

Acute Renal Failure - American Family Physicia

Acute renal failure (ARF), also known as acute kidney failure or acute kidney injury, is the abrupt loss of kidney function.The glomerular filtration rate (GFR) falls over a period of hours to a few days and is accompanied by concomitant rise in serum creatinine and urea nitrogen. If left untreated, acute renal failure may complicate to chronic renal failure Types of Kidney Disease. There are two types of kidney failure in cats. Each has different causes, treatments, and outlooks. Acute renal failure develops suddenly, over a matter of days or weeks. It happens in cats of all ages and is usually the result of: Poisons, which are the most common cause of acute renal failure Chronic kidney disease (CKD), also known as chronic kidney failure, means a gradual loss of kidney function over time. Chronic means the damage happens slowly and over a long period of time. Early detection can help prevent the progression of kidney disease. Learn about causes, symptoms, testing, and more

Acute kidney injury (also called acute renal failure) nursing NCLEX review lecture on the nursing management, stages, pathophysiology, and causes (prerenal,. Hyponatremia can be the result of illnesses and medications. Some causes that may be related to kidney disease include: Kidney failure - the kidneys cannot get rid of extra fluid from the body; Congestive heart failure - excess fluid builds up in the body; Diuretics (water pills) - makes the body get rid of more sodium in the urin Acute renal failure (ARF) or acute kidney failure refers to the sudden failure of the kidneys to perform normal filtration duties. ARF leads to accumulation of toxins and other metabolic wastes in the bloodstream, dehydration, electrolyte imbalances, and disturbances in the acid-base balance of the blood. The initial prognosis is guarded for all cases of ARF. If the cause is an infection. Coronavirus: Kidney Damage Caused by COVID-19. COVID-19 — the disease caused by the coronavirus that's led to the global pandemic —is known to damage the lungs. But, as more people become infected, more understanding of the disease emerges. Doctors and researchers are finding that this coronavirus — officially called SARS-CoV-2—can. Prerenal failure is the most common type of acute kidney failures. This article discusses the causes, symptoms, and treatment regarding the same. Acute Renal Failure (ARF) is the sudden loss of kidney functionality. The causes of ARF are classified into three categories such as prerenal, renal, and postrenal

Almost 1 in 2 U.S. adults—or about 108 million people—have high blood pressure. 1. More than 1 in 7 U.S. adults—or about 37 million people—may have chronic kidney disease (CKD). 2. High blood pressure is the second leading cause of kidney failure in the United States after diabetes, as illustrated in Figure 1. 2 On other occasions, acute renal failure will have no signs and symptoms and would only be seen via other tests of a different purpose. Causes and Risk Factors. There are three main causes of acute renal failure: condition that decreases blood flow to the kidneys, direct kidney damage, and blocked ureters. Decreased blood flow to the kidneys Chronic kidney disease (CKD) is usually first suspected when serum creatinine rises. The initial step is to determine whether the renal failure is acute, chronic, or acute superimposed on chronic (ie, an acute disease that further compromises renal function in a patient with CKD—see table Distinguishing Acute Kidney Injury From Chronic Kidney Disease) One of the causes of kidney failure is diabetes mellitus, a condition characterised by high blood glucose (sugar) levels. Over time, the high levels of sugar in the blood damage the millions of tiny filtering units within each kidney. There is no cure, and treatment must become ever more aggressive as the kidneys deteriorate towards failure

Pathophysiology of acute renal failure in idiopatic

Acute renal failure (ARF) is a life-threatening disorder that can affect cats of any age. Acute renal failure may be caused by decreased blood flow to the kidneys (called ischemia) or exposure to certain drugs or chemicals that are toxic to the kidneys. Low blood flow to the kidneys may occur during anesthesia and surgery, and some drugs such. Acute renal failure may be caused by multiple conditions including those which are due to some direct hemodynamic or nephrotoxic insult. In considering the pathophysiology of these entities, it seems appropriate to differentiate between the initiating and the maintenance phase of the disorder Acute kidney failure causes may include, but are not limited to, the following: Myocardial infarction - a heart attack may lead to temporary kidney failure. Rhabdomyolysis - kidney damage that can occur from muscle breakdown. This condition can occur from severe dehydration, infection, or other causes. Decreased blood flow to the kidneys for a.

The Pathophysiology of Acute Renal Failure - Critical Care

Acute Renal Failure Nursing Care and Management: Study Guid

Chronic Kidney Disease Pathophysiology (EASY!!) | Full Nursing LectureHere's an easy breakdown of Chronic Kidney Disease (aka Chronic Renal Failure). This is one of the must-know topics that you will cover in nursing school.We will break it down super simple and go through the what is happening and WHY! Trust me, understanding the pathophysiology behind [ Oh's Manual: Chapter 47 (pp. 535) Acute kidney injury by Rinaldo Bellomo Schrier, Robert W., et al. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. The Journal of clinical investigation 114.1 (2004): 5-14 Diabetes and high blood pressure are the two leading causes of kidney disease. They are also considered risk factors, because having either condition increases your risk of getting kidney disease. Diabetes Diabetes is the #1 cause of kidney disease. Diabetes is a disease that causes your body to have trouble making or using insulin

Acute renal failure is when a person's kidneys are not working as well as they once did. This usually happens very suddenly over several hours or up to 2 days In this lesson, we discussed one of three causes of acute renal failure. Postrenal failure is a type of acute renal failure that occurs as a result of obstruction to urine outflow. It can occur as.

15 Symptoms of Kidney Disease. 1. Fatigue - being tired all of the time. Why this happens: Healthy kidneys make a hormone called erythropoietin (a-rith'- ro-po'- uh-tin), or EPO, that tells your body to make oxygen-carrying red blood cells. As the kidneys fail, they make less EPO. With fewer red blood cells to carry oxygen, your muscles and. Acute kidney injury, also called acute renal failure, is more commonly reversible than chronic kidney failure. Acute kidney injury (AKI) is usually caused by an event that leads to kidney malfunction, such as dehydration , blood loss from major surgery or injury, or the use of medicines This is one of the reasons why only 10% of people with chronic kidney disease know that they have it, says Dr. Joseph Vassalotti, Chief Medical Officer at the National Kidney Foundation. While the only way to know for sure if you have kidney disease is to get tested, Dr. Vassalotti shares 10 possible signs you may have kidney disease

Chronic Kidney Disease (CKD) — Pathophysiology and Diagnosi

Acute kidney injury (AKI), which is previously called acute renal failure, is a rapid loss of kidney function which occur within 6 months without treatment. Causes of AKI include those that damage the kidneys, leading to the inability of the kidneys to perform their function. The kidneys are responsible for filtering the blood, eliminating. Diabetic kidney disease develops in approximately 40% of patients who are diabetic and is the leading cause of CKD worldwide. Although ESRD may be the most recognizable consequence of diabetic kidney disease, the majority of patients actually die from cardiovascular diseases and infections before needing kidney replacement therapy. The natural history of diabetic kidney disease includes. Pathophysiology lecture about acute renal failure including pre-renal, intra-renal, and post-renal causes Acute kidney injury happens when the kidneys are suddenly damaged, by things like certain medications, sepsis, or a lack of blood flow. This damage can be reversible, as long as it is treated promptly. The causes of acute kidney injury are divided up into 3 main categories: Prerenal. Intrarenal Causes of shortness of breath in kidney failure. In kidney failure, the most common causes of shortness of breath include: 1. Metabolic Acidosis: kidney is a bean-shaped organ with responsibilty of keeping acid-base balance. When kidney function is impaired seriously because of kidney failure, disturbance of acid-base occurs

Chronic kidney disease - Symptoms and causes - Mayo Clini

Polycystic kidney disease: a genetic disease that causes many cysts to grow in the kidneys Glomerulonephritis: a disease that causes irritation to the tiny blood vessels (glomeruli) in your kidneys Acute kidney injury: kidney failure that happens very quickly, often because of injuries, major blood loss or reactions to medicine Kidney (Renal) failure (acute or chronic) occurs when the kidneys no longer function well and the end stage of kidney failure. Some people have symptoms of kidney failure while others do not; however whey they do occur they include shortness of breath, generalized swelling, and congestive heart failure. Causes of acute and chronic kidney failure include medications, cancer, and cirrhosis

Acute Kidney Failure: Causes, Risk Factors, and Symptom

Chronic kidney disease (CKD)—or chronic renal failure (CRF), as it was historically termed—is a term that encompasses all degrees of decreased renal function, from damaged-at risk through mild, moderate, and severe chronic kidney failure. CKD is a worldwide public health problem The most common form of kidney disease is chronic kidney disease (CKD).It develops when kidneys become permanently damaged. About 37 million people are estimated to have CKD, and most don't know they have it, according to the Centers for Disease Control (CDC). 1 You can find kidney disease in an earlier stage (before permanent damage occurs) by seeing your primary care doctor Alcoholism, heart disease, hepatitis C, and HIV are also causes of kidney disease . When the kidneys become damaged and are unable to function properly, fluid can build up in the body and waste.

The Pathophysiology of Acute Renal Failure SpringerLin

https://www.facebook.com/ArmandoHasudunganSupport me: http://www.patreon.com/armandoInstagram:http://instagram.com/armandohasudunganTwitter:https://twitter.c.. Acute renal failure can be due to many different causes. Generally these causes can be divided into three categories. Pre-renal means the cause is before the kidney or glomerulus. Generally, this is caused by a decrease in the amount of blood that gets to the kidney. Examples include heart failure, liver failure, shock Hence, renal disease might be both a cause and consequence of hypertension, forming a vicious circle whereby hypertension causes kidney damage, which then exacerbates the high blood pressure. Hypertensive nephrosclerosis is characterized by arterial wall thickening, loss of renal autoregulation, glomerulosclerosis, tubular atrophy and. Pathophysiology of Chronic Kidney Disease. Chronic kidney disease (CKD) is a venerable, increasing decline of the functions of kidneys. The warning signs and symptoms build up gradually and comprise of vomiting, nausea, dysguesia, anorexia, fatigue, nocturia, pruritis, stomatitis, lassitude, reduced psychological perception, cramps and twitches in muscles, retention of water, under nutrition. Usually, postrenal acute renal failure is caused by some kind of obstruction in the bladder or its related passageways. Kidney stones or tumors in the ureters (the tubes connecting your kidneys to your bladder) can block waste from passing into the bladder. Also, anything that causes an obstruction in the bladder itself, such as an enlarged.

Chronic kidney disease (CKD) McMaster Pathophysiology Revie

Acute renal failure. When kidney function suddenly decreases (within hours or days), this is known as acute renal failure. It is usually related to toxins or infections. Chronic renal failure. If the loss of kidney function is gradual (over weeks, months or years), it's referred to as chronic renal failure Therefore, one of the earliest clinical signs of kidney failure is increased water consumption and urination, and is called compensated renal failure.After approximately 2/3 of the kidney tissue is destroyed, there is a rapid rise in waste products in the bloodstream and an apparent sudden onset of severe disease Chronic kidney disease is defined as kidney disease that has been present for months to years. Chronic renal disease (CRD), chronic renal failure (CRF), and chronic renal insufficiency refer to the same condition. CKD is not a single disease. There are many different causes of CKD but by the time the animal shows signs of kidney disease the. RENAL FAILURE 3. Explain Michael's clinical manifestations based on the underlying pathophysiology of CKD The first of Michael's chronic kidney disease (CKD) manifestations is uremia, resulting from the buildup of waste products and excess fluids. He is also experiencing low urine output of 200cc/24hours, gross proteinuria, a specific gravity of 1.011, and a presence of multiple cell casts Support me: ️ Buy PDFs: http://armandoh.org/shop Patreon: http://www.patreon.com/armando Buy shirts: https://teespring.com/stores/ah-7Social media: ..

Acute Kidney (Renal) Failure: Symptoms, Causes, Treatment

Acute kidney injury (AKI), previously called acute renal failure (ARF), is a rapidly progressive loss of renal function, generally characterized by oliguria (decreased urine production, quantified as less than 400 mL per day in adults, less than 0.5 mL/kg/h in children or less than 1 mL/kg/h in infants); and fluid and electrolyte imbalance.AKI can result from a variety of causes, generally. Unfortunately, renal failure or nephropathy (commonly referred to as kidney failure) and unmanaged diabetes go hand in hand. In addition, 50 percent of people with diabetes will experience some form of kidney damage in their lifetime, even if they never experience kidney failure or end up on dialysis Chronic renal failure, also called chronic kidney disease, nursing NCLEX review lecture on the pathophysiology, symptoms, stages, and causes.Chronic kidney d..